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Structure of the human M1 muscarinic acetylcholine receptor bound to antagonist Tiotropium

NIAID Data Ecosystem2026-05-02 收录

G蛋白偶联受体分析

药物-靶点结合

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https://www.rcsb.org/structure/5CXV 数据链接链接失效反馈

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Structure of the human M1 muscarinic acetylcholine receptor bound to antagonist Tiotropium

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创建时间：

2024-11-20

G蛋白偶联受体分析

蛋白质序列特征

Shaded features are ones for which the PS≥0.5. The amino acid, exposed α-helix, buried α-helix and β strand features are all proportions (e.g. the Alanine feature for a protein is the number of alanin

NIAID Data Ecosystem30

Route to Prolonged Residence Time at the Histamine H 1 Receptor: Growing from Desloratadine to Rupatadine

药物-靶点结合

抗菌药物优化

Drug–target binding kinetics are an important predictor of in vivo drug efficacy, yet the relationship between ligand structures and their binding kinetics is often poorly understood. We show that bot

NIAID Data Ecosystem20

MicroED structure of the human adenosine receptor at 2.8A

G蛋白偶联受体分析

微晶电子衍射

MicroED structure of the human adenosine receptor at 2.8A

NIAID Data Ecosystem10

Crystal structure of gamma-glutamyltranspeptidase from Bacillus subtilis (crystal soaked for 3min. in acivicin soln. )

晶体结构解析

药物-靶点结合

Crystal structure of gamma-glutamyltranspeptidase from Bacillus subtilis (crystal soaked for 3min. in acivicin soln. ) Descriptor: Gamma-glutamyltranspeptidase large chain, Gamma-glutamyltranspeptidas

Protein Data Bank Japan2023-11-08 更新20

Cryo-EM of Sphingosine 1-phosphate receptor 1 / Gi complex bound to FTY720p

G蛋白偶联受体分析

偏向性激动剂机制研究

Cryo-EM of Sphingosine 1-phosphate receptor 1 / Gi complex bound to FTY720p Descriptor: (2~{S})-2-azanyl-4-(4-octylphenyl)-2-[[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxymethyl]butan-1-ol, Guani

Protein Data Bank Japan2024-11-06 更新10

Structure of the human M1 muscarinic acetylcholine receptor bound to antagonist Tiotropium

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