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CK2-mediated DEK Phosphorylation Drives PBX3 Overexpression: A Core Event in Hematopoietic Stem Cell-to-Leukemia Stem Cell Transformation

NIAID Data Ecosystem2026-05-10 收录

白血病干细胞转化

磷酸化调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE309285 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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创建时间：

2025-09-30

植物器官再生

磷酸化调控

Reversible protein phosphorylation is a post-translational modification involved in virtually all plant processes, as it mediates protein activity and signal transduction. Here, we probe dynamic prote

NIAID Data Ecosystem30

The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation

先天免疫信号通路

磷酸化调控

The activity of Cullin-RING ubiquitin E3 ligases (CRL) is regulated by NEDD8 modification. DCN-like proteins promote Cullin neddylation as scaffold-like E3s. One DCNL, DCNL5, is highly expressed in im

Figshare2018-06-29 更新20

Protein phosphorylation in pancreatic islets induced by 3-phosphoglycerate and 2-phosphoglycerate.

磷酸化调控

代谢信号通路

We have shown previously that 3-phosphoglycerate, which is a glycolytic metabolite of glucose, induces protein phosphorylation in bovine and rat brain and in rat heart, kidney, liver, lung, and whole

PubMed Central10

Phosphorylation level of SIRT1 in proliferating and senescent IMR90 cells

细胞衰老机制

磷酸化调控

Mammalian SIRT1 is a central regulator of metabolism and aging. This project is to analyze global phosphorylation levels of mammalian SIRT1 in proliferating and senescence states using human lung fibr

NIAID Data Ecosystem30

Sulfolobus islandicus REY15A Raw sequence reads

DNA损伤响应

磷酸化调控

Reversible protein phosphorylation, the main mechanism of eukaryotic DNA damage signaling, has attracted much less attention in prokaryotic DNA damage response. In this study, we found that Orc1-2 pho

NIAID Data Ecosystem20

CK2-mediated DEK Phosphorylation Drives PBX3 Overexpression: A Core Event in Hematopoietic Stem Cell-to-Leukemia Stem Cell Transformation

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