Figure 6

Raw images are currently being uploaded to Image Data Resource. The link to this image resource will be provided here by April 2022, at the latest. Here we provide the exported colocalization data used to generate plots in Figure 6, and the original images that were cropped for display in the paper. Figure 6a -Example cropped images for each cell line treated with each BH3 mimetic. Data is organized into folders according to date acquired. Original image and corresponding image with adjusted intensity/contrast (displayed in this paper) are included. -See powerpoint for an additional observation: AT-101 causes CBclW to form small circles in the cell. Unknown mechanism or role in apoptosis. Figure 6b -Colocalization analysis results from BMK-DKO cells expressing CBcl-XL, CBcl-2, CMcl-1, or CBclW and treated with BH3 mimetics. Original image data available upon request.原始图像目前正在上传至图像数据资源库（Image Data Resource）。本图像数据集的资源链接最迟将于2022年4月前在此处公布。本次我们提供了用于生成图6绘图的导出共定位数据，以及论文中用于展示的裁剪原始图像。 - 图6a：经每种BH3模拟物（BH3 mimetic）处理的各细胞系的示例裁剪图像。数据按采集日期分文件夹存储。包含原始图像以及经强度/对比度调整后的对应图像（即本文中展示的图像）。 - 补充观测详见PowerPoint演示文稿：AT-101可诱导CBclW在细胞内形成小型环状结构，其具体作用机制及在细胞凋亡中的功能尚不明确。 - 图6b：表达CBcl-XL、CBcl-2、CMcl-1或CBclW，且经BH3模拟物处理的BMK-DKO细胞的共定位分析结果。原始图像数据可应要求提供。