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Effect of various compounds on ATPase activity of purified Pdr11pa.

Figshare2017-09-19 更新2026-04-29 收录

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https://figshare.com/articles/dataset/Effect_of_various_compounds_on_ATPase_activity_of_purified_Pdr11p_sup_a_sup_/5416036 数据链接链接失效反馈

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Effect of various compounds on ATPase activity of purified Pdr11pa.

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创建时间：

2017-09-19

动力学研究

信号传导机制

Enzymerhodopsins represent a recently discovered class of rhodopsins which includes histidine kinase rhodopsin, rhodopsin phosphodiesterases and rhodopsin guanylyl cyclases (RGCs). The regulatory infl

DataONE2021-10-20 更新120

A preclinical candidate of cyclophilin D inhibition improves alcohol-associated liver injury

酒精性肝病

肿瘤药物靶点验证

Currently, no therapies are approved for alcohol-associated liver disease (ALD). Here, we identify cyclophilin D (CypD) as a critical mediator in the progression of ALD. We observe elevated expression

NIAID Data Ecosystem110

Activities of the different FXR agonists in different assay systems.

受体激动剂筛选

肿瘤药物靶点验证

(A) Activities in the biochemical TR-FRET assay using the human FXR-LBD. (B) Activities in Gal4-FXR-LBD fusion cellular reporter assays using mouse (mFXR) and human FXR-LBDs (hFXR). Efficacy is provid

Figshare2015-12-02 更新30

Quantitative Interpretation of Intracellular Drug Binding and Kinetics Using the Cellular Thermal Shift Assay

肿瘤药物靶点验证

热位移分析

Evidence of physical interaction with the target protein is essential in the development of chemical probes and drugs. The cellular thermal shift assay (CETSA) allows evaluation of drug binding in liv

NIAID Data Ecosystem110

AMPK inhibitors may be potential drugs for STING-induced inflammatory diseases.

肿瘤药物靶点验证

炎症基因表达

AMPK inhibitors suppress inflammatory gene expression induced by STING R284S variants. STING R284S variant was expressed in STING-/- MEF cells. RNA was extracted from the MEF cells after treated with

NIAID Data Ecosystem40

Effect of various compounds on ATPase activity of purified Pdr11pa.

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