Data from Head and Neck Cancer CT Atlas (Head-Neck-CT-Atlas)

This project screened 2840 consecutive patients with HNSCC treated with curative-intent RT at MD Anderson Cancer Center from 2003 to 2013. Patients with whole-body PET-CT or abdominal CT scans both before and after RT (n=215) were selected for the cohort. De-identified diagnostic imaging, radiation treatment planning, and follow up imaging are provided. Using cross sectional imaging, total body skeletal muscle and adipose content were calculated before and after treatment. All imaging data are subject- and date-matched to clinical data from each patient, including demographics, risk factors, grade, stage, recurrence, and survival. Open access to these data allows for inter-institutional comparisons of complete RT details in non-randomized patient populations, allowing for a more granular understanding of three dimensional factors that influence treatment effectiveness and toxicity sparing.2003年至2013年间，本研究于MD安德森癌症中心（MD Anderson Cancer Center）筛选了2840例连续入组的、接受根治性放射治疗（Radiation Therapy, RT）的头颈部鳞状细胞癌（Head and Neck Squamous Cell Carcinoma, HNSCC）患者。最终，本队列纳入了215例在放射治疗前后均完成全身PET-CT或腹部CT扫描的患者。本数据集包含去标识化的诊断影像、放射治疗计划影像及随访影像资料。研究人员通过横断面影像计算了受试者治疗前后的全身骨骼肌与脂肪组织含量。所有影像数据均按受试者及日期与每位患者的临床数据完成匹配关联，临床数据涵盖人口统计学信息、危险因素、肿瘤分级、临床分期、复发情况及生存结局。该数据集的开放获取特性，支持在非随机化患者群体中开展跨机构的完整放射治疗细节对比研究，从而更细致地解析影响治疗疗效与毒性规避的三维相关因素。

搜集汇总

背景与挑战

背景概述

该数据集是头颈癌CT图谱数据，包含2003-2013年间MD Anderson癌症中心2840名头颈鳞状细胞癌患者中筛选的215名患者的去标识化影像和临床数据，涵盖放疗前后的CT/PET-CT扫描、治疗计划、骨骼肌和脂肪含量计算，以及匹配的人口统计学和临床结局信息，支持跨机构研究以深入分析放疗效果和毒副作用的三维影响因素。