Genotypic Clustering from Open Targets

Zenodo2024-05-27 更新2026-04-07 收录

药物靶点发现

基因型聚类分析

数据链接：

https://zenodo.org/doi/10.5281/zenodo.11361053 数据链接链接失效反馈

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资源简介：

These data are from genotypic clustering from Open Targets. Results from Pearson's correlation and Hypergeometric tests are also added here.

创建时间：

2024-05-27

Crystal structure of the first bromodomain of human BRD4 in complex with SJ001010551-2

蛋白质晶体学

药物靶点发现

Crystal structure of the first bromodomain of human BRD4 in complex with SJ001010551-2 Descriptor: 1,2-ETHANEDIOL, 2-[(6S,10S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a]

Protein Data Bank Japan2023-10-18 更新50

crystal structure of compound 16 bound to MDM2(17-111), {(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(PYRROLIDIN-1-YLSULFONYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID

结构生物学

药物靶点发现

Protein Data Bank Japan2024-02-28 更新10

Plasmodium falciparum apical membrane antigen 3D7

疟原虫抗原

药物靶点发现

Plasmodium falciparum apical membrane antigen 3D7

NIAID Data Ecosystem00

CEP-701 KINOMEscan

酶抑制活性筛选

药物靶点发现

The KINOMEscan assay platform is based on a competition binding assay that is run for a compound of interest against each of a panel of 442 kinases. The assay has three components: a kinase-tagged pha

NIAID Data Ecosystem10

Identification of brain metastasis vulnerabilities using METPlatform

脑转移瘤治疗

药物靶点发现

Exclusion of cancer patients with brain metastases from clinical trials is a major cause of the limited therapeutic options available for secondary brain tumors. Here, we report a novel drug-screening

NIAID Data Ecosystem10

Genotypic Clustering from Open Targets

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