In MTN-007, a phase 1, randomized, double-blinded rectal microbicide trial, we used systems genomics/proteomics to determine the effect of tenofovir 1% gel, nonoxynol-9 2% gel, placebo gel or no treat
Cathelicidin-RC1 was dissolved in sterile deionized water to an ultimate concentration of 2 mg/ml and stored at 37°C for 0 to 96 h. At different time intervals, cathelicidin-RC1 samples were taken and
a—MIC represents the lowest peptide concentration required to kill entire bacteria, NA-not active up to the highest concentration tested. Antibacterial and hemolytic activity of synthetic B1CTcu5 and