耳蜗组织病理

组织病理技术面向耳蜗-电极交互作用模型验证研究，组织切片技术是内耳微细观察研究的一种方法，石蜡切片在制作过程中，石蜡密度小、填充性不强、切片难度较大等，目前较多应用于科研实验。 小型猪耳蜗植入电极后将标本放在4%多聚甲醛固定24-48小时，用甲酸脱钙5-7天，将其进行脱水5-7天，最后进行染色、切片、电镜扫描等。为了对所造成的创伤程度进行标准化，使用了Eshraghi等人最近发表的分级方案。将植入耳蜗电极后拔出的小型猪耳蜗进行病理切片，观察组织病理结果。数据量：11.35GB。This work applies histopathological techniques for the validation study of the cochlea-electrode interaction model. Tissue sectioning is a standard method for fine morphological observation of the inner ear. During the preparation of paraffin sections, challenges including low paraffin density, insufficient filling capacity, and high sectioning difficulty are commonly faced; nonetheless, paraffin sectioning remains widely utilized in current scientific research experiments. For specimens obtained from miniature pigs after cochlear electrode implantation, they were fixed in 4% paraformaldehyde for 24 to 48 hours, decalcified with formic acid for 5 to 7 days, dehydrated for another 5 to 7 days, and subsequently underwent staining, sectioning, and electron microscopy scanning, among other processing steps. To standardize the evaluation of the induced trauma severity, the grading scheme recently published by Eshraghi et al. was employed. Cochleae extracted from miniature pigs following electrode implantation were prepared into pathological sections for histopathological observation. The total size of this dataset is 11.35 GB.

搜集汇总

背景与挑战

背景概述

该数据集包含小型猪耳蜗植入电极后的组织病理切片数据，用于验证耳蜗-电极交互作用模型，涉及染色、切片和电镜扫描等过程。数据量为11.35GB，来源于国家重点研发计划项目'人工耳蜗微创植入机器人系统研究'。