Role of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes

ChEBI2010-05-22 更新2026-07-21 收录

毒理基因组学

肝脏代谢调控

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Role of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes

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2010-05-22

Tricresyl Phosphate (CAS No. 1330-78-5): 5-Day Rat Gavage Toxicogenomic Study

毒理基因组学

毒性评估

Tricresyl Phosphate (TCP) is an organophosphate flame retardant currently on the market and used as a replacement for phased-out polybrominated diphenyl ethers. Toxicity information on this class of c

NIAID Data Ecosystem40

Zinc Transporter ZIP14 Functions in Hepatic Zinc, Iron and Glucose Homeostasis during the Innate Immune Response (Endotoxemia)

肝脏代谢调控

先天免疫应答中的金属离子转运

ZIP14 (slc39A14) is a zinc transporter induced in response to pro-inflammatory stimuli. ZIP14 induction accompanies the reduction in serum zinc (hypozincemia) of acute inflammation. ZIP14 can transpor

NIAID Data Ecosystem40

Species difference in gene expression effect of trichloroethylene (TCE) between mouse and rat (rat). Species difference in gene expression effect of trichloroethylene (TCE) between mouse and rat (rat)

毒理基因组学

物种差异致癌机制

TCE is a non-genotoxic hepatocarcinogen in mouse, but not in rat or human. Extrapolation of data from laboratory animals to humans is difficult due to species-specific differences. To identify molecul

NIAID Data Ecosystem10

Toxicogenomics and phenotypic characterization of adult female zebrafish liver treated with chloroaniline. Danio rerio

毒理基因组学

毒性评估

We performed microarray-based expression profiling on liver of male zebrafish exposed to 30 µg/L of chloroaniline for 8-96 h, to identify global transcriptional programs and biological pathways involv

NIAID Data Ecosystem40

Whole genome expression analysis in the third-instar larval midgut of Drosophila melanogaster. Drosophila melanogaster

毒理基因组学

果蝇基因表达

Survival of insects on a substrate containing toxic substances such as plant secondary metabolites or insecticides is dependent on the metabolism or excretion of those xenobiotics. The primary sites o

NIAID Data Ecosystem30

Role of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes

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