Mixed tailing by TUT3 and TUT5 shields mRNA from rapid deadenylation
收藏NIAID Data Ecosystem2026-03-11 收录
官方服务:
资源简介:
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景:
创建时间:
2019-09-08
相关数据集
m6A sites in the coding region trigger translation-dependent mRNA decay
m6A is the predominant internal RNA modification in messenger RNAs of eukaryotes (mRNAs), and plays a critical role in RNA stability. In this study, we reveal that m6A sites in the coding sequences (C
NIAID Data Ecosystem80
Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA.
The abundance of the mRNA for human triosephosphate isomerase (TPI) is decreased to 20-30% of normal by frameshift and nonsense mutations that prematurely terminate translation within the first three-
PubMed Central1993-01-15 更新60
TNF-induced dynamic regulation of mRNA stabilome in rheumatoid arthritis fibroblast-like synoviocytes. Homo sapiens
During rheumatoid arthritis (RA), TNF activates fibroblast-like synoviocytes (FLS) inducing in a temporal order a constellation of genes, which perpetuate synovial inflammation. Although the molecular
NIAID Data Ecosystem40
Mixed tailing by TUT3 and TUT5 shields mRNA from rapid deadenylation [TAIL-Seq]
RNA tails play integral roles in the control of mRNA translation and decay. Guanylation of poly(A) tail was discovered recently, yet the enzymology and function remain obscure. Here we identify TUT3 (
NIAID Data Ecosystem80
Integration of human papillomavirus type 16 DNA into the human genome leads to increased stability of E6 and E7 mRNAs: implications for cervical carcinogenesis.
In many cervical cancers, human papillomavirus type 16 (HPV-16) DNA genomes are found to be integrated into the host chromosome. In this study, we demonstrate that integration of HPV-16 DNA leads to i
PubMed Central1995-02-28 更新60



