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Pancreatic Differentiation of stem cells reveals pathogenesis of a syndrome of Ketosis-Prone Diabetes

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NIAID Data Ecosystem2026-03-13 收录
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We describe an unusual course of Ketosis Prone Diabetes and investigate potential mechanisms using induced pluripotent stem cell technology with high throughput mRNA sequencing and validation of a lecuine sensitive mTOR pathway. Overall design: Comparison of patient versus control iPS cells and differentiation to pancreatic progenitors with metabolomics and rna-sequencing

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2021-12-01
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