Pharmacodynamic parameter estimates and confidence interval for the final model and Bootstrap (1000 simulations) for patient state index (PSI) and suppression ratio (SR).
‡A = 10−3 (L cm−3)6.1510−6 (cm2)1109 (cells/L).¥Measured = Fold change between the resistant and sensitive cell lines (as determined by basal SOD and G6PD activity) multiplied by the parameter value f
Trials of the early bactericidal activity (EBA) of tuberculosis (TB) treatments assess the decline, during the first few days to weeks of treatment, in colony forming unit (CFU) count of Mycobacterium
