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Genome-wide profiling of the functional DNA methylation landscape at base-pair resolution in human cancer types. Genome-wide profiling of the functional DNA methylation landscape at base-pair resolution in human cancer types

NIAID Data Ecosystem2026-03-08 收录

癌症表观遗传学

DNA甲基化图谱

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA230572 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2013-11-12

癌症表观遗传学

癌症生物标志物

Background: Abnormal epigenetic alterations can contribute to the development of human malignancies. Identification of these alterations for early screening and prognosis of clear cell renal cell carc

NIAID Data Ecosystem30

The NCI-60 Methylome and Its Integration into CellMiner

癌症表观遗传学

DNA甲基化分析

Methylation assay of cell lines from 9 different cancer tissue of origin types (Breast, Central Nervous System, Colon, Leukemia, Melanoma, Non-Small Cell Lung, Ovarian, Prostate, Renal) from NCI-60 pa

NIAID Data Ecosystem10

Peripheral blood DNA methylation analysis reveals epigenetic marks associated with hereditary breast and ovarian cancer risk. 231 HBOC patients

癌症表观遗传学

遗传性癌症风险

Hereditary breast and ovarian cancer syndrome (HBOC) is the most prevalent form of hereditary breast cancer (BC) associated with pathogenic variants in several genes, revealing a significant locus het

NIAID Data Ecosystem10

Effect of overexpression of wildtype (WT), triple acetylation-deficient mutant (K3R), or triple acetylation-mimetic mutant (K3Q) SIRT6 on gene expression in human non-small cell lung cancer cells

癌症表观遗传学

SIRT6功能研究

To investigate how the acetylation state of SIRT6 affects its tumor suppressive function in non-small cell lung cancer (NSCLC) cells, we established A549 and H1299 NSCLC cell lines stably expressing e

NIAID Data Ecosystem20

Additional file 6 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

癌症表观遗传学

药物敏感性预测

Additional file 6: Supplementary Table 6. Candidate genes with methylation probes that had correlations with log(IC50) of candidate antitumor agents satisfying pFDR < 0.15.

Figshare2020-06-26 更新10

Genome-wide profiling of the functional DNA methylation landscape at base-pair resolution in human cancer types. Genome-wide profiling of the functional DNA methylation landscape at base-pair resolution in human cancer types

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