This study examined large renal tubule extracellular vesicles (LRT-EVs) isolated from urine of a 5/6 nephrectomy (5/6Nx) rat model that recapitulates many elements of human chronic kidney disease (CKD
Contribution of bone marrow-derived cells to in situ engineered tissue capsules in a rat model of chronic kidney disease. Tissue engineered blood vessels (TEBVs) hold great promise for clinical use in
We studied a murine AVF in mice with chronic kidney disease (CKD). Venous mRNA of 7 day sham and AVF-CKD mice were sequenced using an Illumina HiSeq 2000.
We compared transcriptome profiles of WT kidneys with that of RNLS KO kidneys. We also compared transcriptome profiles of healthy kidneys to CKD kidneys. Our study represents the first detailed transc
*: p<0.05 vs. vehicle treated CRF rats, same time point. °: p<0.05 vs. week 0, same treatment group. Serum biochemistry of vehicle versus 185 mg/kg CaMg treated adenine-induced CRF rats.