Investigating conformational changes of BmrA reconstituted into invisible-in-...

The ABC transporter BmrA is involved in the efflux of drugs and antibiotics in Bacillus subtilis (e.g. ethidium, doxorubicin, cervimycin C). Large conformational changes must...ATP结合盒转运蛋白（ABC transporter）BmrA参与枯草芽孢杆菌（Bacillus subtilis）内药物与抗生素的外排过程，其底物包括乙锭（ethidium）、多柔比星（doxorubicin）以及西维霉素C（cervimycin C）等。该蛋白必须发生大规模构象变化……