Compounds that were included in the model training sets are marked as ‘T’, compounds predicted to have sub 10 μM binding affinity are marked as ‘+’, and compounds predicted to have > 10 μM binding aff
(A) Activities in the biochemical TR-FRET assay using the human FXR-LBD. (B) Activities in Gal4-FXR-LBD fusion cellular reporter assays using mouse (mFXR) and human FXR-LBDs (hFXR). Efficacy is provid
BackgroundSepsis-induced myopathy (SIM) is a severe complication of sepsis, leading to significant muscle dysfunction and increased mortality. The molecular mechanisms underlying SIM remain poorly und
CovMulNet19 is a comprehensive network containing all available known interactions involving SARS-CoV-2 proteins, interacting-human proteins, diseases and symptoms that are related to these human prot
This dataset is derived from PubChem BioAssay AID 743077, titled "qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway". The original assay