Brucella melitensis: A nasty bug with hidden credentials for virulence

Name: Brucella melitensis: A nasty bug with hidden credentials for virulence
Creator: National Academy of Sciences
Published: 2002-01-08T00:00:00+08:00

PubMed Central2002-01-08 更新2026-05-16 收录

毒力机制

布鲁氏菌病原学

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https://pmc.ncbi.nlm.nih.gov/articles/PMC117501/数据链接链接失效反馈

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Brucella melitensis: A nasty bug with hidden credentials for virulence

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National Academy of Sciences

创建时间：

2002-01-08

Phosphorylation state and DNA-binding activity of c-Jun depend on the intracellular concentration of binding sites.

转录因子调控

磷酸化信号传导

The DNA-binding activity of c-Jun expressed in eukaryotic cells was found to be markedly enhanced if the intracellular concentration of binding sites for this transcription factor was increased by cot

PubMed Central1992-12-01 更新10

A regulatory cascade hypothesis for mammalian sex determination: SRY represses a negative regulator of male development.

性别决定遗传机制

SRY基因调控

The mammalian Y chromosome carries the SRY gene, which determines testis formation. Here we review data on individuals who are XX but exhibit male characteristics: some have SRY; others do not. We hav

PubMed Central1993-04-15 更新00

Loligomers: design of de novo peptide-based intracellular vehicles.

肽类药物设计

细胞内靶向递送

Defined branched peptides (loligomers) incorporating cytoplasmic translocation signals, nuclear localization sequences, and fluorescent probes were designed and synthesized to demonstrate the feasibil

PubMed Central1995-03-14 更新00

Identification of the complement iC3b binding site in the beta 2 integrin CR3 (CD11b/CD18).

整合素-补体相互作用

抗炎药物靶点鉴定

The divalent cation-dependent interaction of the beta 2 integrin CR3 (CD11b/CD18) with the major complement opsonic C3 fragment iC3b is an important component of the central role of CR3 in inflammatio

PubMed Central1994-10-25 更新00

The myosin step size: measurement of the unit displacement per ATP hydrolyzed in an in vitro assay.

分子机制

ATP水解耦合

Chemomechanical coupling in muscle contraction may be due to "swinging crossbridges," such that a change in the angle at which the myosin head binds to the actin filament is tightly coupled to release

PubMed Central00

Brucella melitensis: A nasty bug with hidden credentials for virulence

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