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Two new prenylated indole diketopiperazine alkaloids (PIDAs) penicamides A and B (1 and 2) and three new polyketides penicinones A−C (6−8), along with four known compounds deoxybrevianamide E (3), bre
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DataSheet1_Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening.docx
Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective
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Terpenoids from Daphne pedunculata and their cytotoxic activities in vitro
This dataset is the research data of the article titled "Terpenoids from Daphne pedunculata and Their Cytotoxic Activities In Vitro". The highlights of the research are: 1. Three new terpenoids, inclu
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Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity
Compounds 13 and 14 were evaluated against 11 PARP isoforms to reveal that both 13 and 14 were more potent and isoform selective toward inhibiting tankyrases (TNKSs) than the “standard” inhibitor 1 (X
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Table S3 from Dianhydrogalactitol Overcomes Multiple Temozolomide Resistance Mechanisms in Glioblastoma
Screening results T98G TMZ
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