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资源简介：
Cas9 target DNA specificity
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创建时间：
2014-11-14
相关数据集
Off-target profiling of CRISPR-Cas13a
In vitro binding and sequencing experiment to assess off-target tolerances and guide / target specificity profiles for the RNA-guided RNA binding protein CRISPR-Cas13a.
NIAID Data Ecosystem80
Suppression of unwanted CRISPR/Cas9 editing by co-administration of catalytically inactive truncated guide RNAs. Homo sapiens
The goal of this study is to develop a novel method for reducing unwanted genomic editing by CRISPR/Cas9 and improve specificity in a variety of cellular contexts.
NIAID Data Ecosystem60
The specificity of exoCasMINI for gene editing.[Tag-seq]
The exoCasMINI exhibits similar specificity for gene editing. Compared to SpCas9, exoCasMINI also exhibited higher specificity for genomic DNA cleavage at the tested sites. We evaluated the specificit
NIAID Data Ecosystem50
Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2. Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2
We present GuideScan2 for memory-efficient, parallelizable construction of high-specificity CRISPR guide RNA (gRNA) databases and user-friendly design and analysis of individual gRNAs and gRNA librari
NIAID Data Ecosystem70
Genome-wide specificity of dCpf1 cytidine base editors
High-throughput sequencing data of genomic DNA samples from human cells
NIAID Data Ecosystem50
