Metabolites in human biofluids reflect individual physiological body states influenced by various factors. Using liquid chromatography-mass spectrometry (LC-MS), we conducted non-targeted, non-invasiv
Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, un
We isolated small extracellular vesicles (sEVs) from umbilical cord plasma (young EVs, Y-EVs) and from elder donor (old EVs, O-EVs). Then we compared the differentially expressed miRNAs in Y-EVs and O
Aging has been shown to be a strong driver of DNA methylation changes, leading to the development of robust biomarkers in humans and more recently, in mice. This study aimed to generate a novel epigen
