Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation

NIAID Data Ecosystem2026-05-02 收录

核糖体结构

蛋白质翻译

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Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation

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2025-03-19

TDP-43 modulates translation of specific mRNAs linked to neurodegenerative disease. TDP-43 modulates translation of specific mRNAs linked to neurodegenerative disease

神经退行性分子机制

蛋白质翻译

We generated total mRNA libraries and ribosome footprint libraries from motor neuron-like cells (MN1) and primary cortical neurons expressing GFPor pure wild type cells as control, human TDP-43 wild t

NIAID Data Ecosystem60

The crystal structure of the 70S ribosome bound to EF-Tu and tRNA

核糖体结构

蛋白质翻译

The crystal structure of the 70S ribosome bound to EF-Tu and tRNA

NIAID Data Ecosystem50

Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G(P610L)-GDP-Pi)

核糖体结构

蛋白质翻译

Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G(P610L)-GDP-Pi)

NIAID Data Ecosystem20

Inhibition of CBP synergizes with the RNA-dependent mechanisms of azacitidine by limiting protein translation

骨髓增生异常综合征

蛋白质翻译

The nucleotide analogue azacitidine (AZA) interferes with RNA and DNA metabolism and is currently the best treatment option for a subset of patients with high-risk myelodysplastic syndromes. However,

NIAID Data Ecosystem60

Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)

核糖体结构

病毒翻译机制

Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit) Descriptor: 18S ribosomal RNA, 25S ribosomal

Protein Data Bank Japan2025-04-02 更新20

Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation

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