Studies of microbial diversity on Olfr558 WT and KO C57BL/6N mice

Butyrate, a short-chain fatty acid (SCFA) produced by gut microbes, is the ligand that yields the strongest activation of both Olfr558 and OR51E1.To determine if alternations in the gut microbiome of Olfr558 KO mice may contribute to the phenotype, we analyzed 16S rRNA from fecal DNA from Olfr558 WT and KO (females and males). The major phyla show no differences between WT and KO