相关数据集
Nociceptive nerves regulate haematopoietic stem cell mobilization
Nociceptive neuropeptide CGRP acts directly on HSCs via the its receptor RAMP1/CALCRL, to promote egress by activating Gαs/Adenylyl cyclase/cAMP pathway.
干细胞与再生医学数据中心2022-02-20 更新120
Bcl11a Deficiency Leads to Hematopoietic Stem Cell Defects with an Aging-like Phenotype
B cell CLL/lymphoma 11A (BCL11A) is a transcription factor and regulator of hemoglobin switching that has emerged as a promising therapeutic target for sickle cell disease and thalassemia. In the hema
NIAID Data Ecosystem40
A lineage of myelolymphoblastic innate cells unmasked by inactivation of mTOR complex 1
Blockades in hematopoiesis deprive the host of vital blood cells and frequently cause leukemia. Here we show that inactivation of mTORC1 in hematopoietic stem cells by deletion of Raptor unmasked a c
NIAID Data Ecosystem20
The role of histone variant H3.3 regulation by HIRA in hematopoiesis (ATAC-Seq)
Histone variants contribute to the complexity of the chromatin landscape and play an integral role in defining DNA domains and regulating gene expression. The histone H3 variant H3.3 is incorporated i
NIAID Data Ecosystem30
