Rational and scalable strategies to identify small âmolecular glueâ degraders
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
In our effort to characterize putatite novel molecular glues that we found in a phenotypic screen, we wanted to gain a more detailed understanding of the effects of these small-molecules at the trascriptome level. Overall design: KBM7 cells treated for 5h with DMSO, dCeMM-1[Hit4], dCeMM-2[Hit1], dCeMM-3[Hit2], dCeMM-4[Hit8] (10xEC50) and THZ531 (600nM). Triplicates per condition.
创建时间：
2020-08-27
