Started in 2007, the Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-ethnicity (SAPPHIRE) is one of the largest asthma cohort studies in the United States. Its overarching goal is
The STING (stimulator of interferon genes) protein can bind cyclic dinucleotides to activate the production of type I interferons and inflammatory cytokines. The cyclic dinucleotides can be bacterial
‡Nucleotide base (of the pair at each SNP), which is coded as having 0, 1, or 2 copies, is shown in parentheses. *Distance from the center of each SNP-cluster. The DRB1cluster spans 160.7 kb and inclu
