Characteristics of the human IgG1 (A1-D1) and IgG2 (A2-D2) antibodies used in this study including variable light chain (VL) framework type, variable heavy chain (VH) framework type, antigen (Ag) for
This repo contains the sequence dataset for finetuning and model weights including pre-trained meta model and a series of finetuned antibody language models. The antibody language models were used in
aThe starting structures used for IPRO designs. GL in the parentheses indicate the structure is germline and AM is for affinity maturation.bThe number of mutations identified by comparing GL and AM an
Antibody-based therapies hold promise for a safe and efficient treatment of cancer. The identification of target tumor cells through a specific antigen enriched on their surface and the subsequent del