Efficient Synthesis of Chiral 2,2′-Bipyrrolidines by an <i>anti</i>-Selective Alkene Diamination
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The rapid and efficient construction of complex chiral bicyclic amines is possible using a novel alkene diamination reaction. Electrophilic iodinating agents promote the intramolecular anti-selective diamination of alkenes and allow the efficient synthesis of chiral amines such as trans-bipyrrolidines.
创建时间:
2012-12-07



