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Transcriptomic profiling of simvastatin-treated human umbilical vein endothelial cells

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NIAID Data Ecosystem2026-03-13 收录
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We report that simvastatin induces an immunoregulatory transcriptional profile in endothelial cells that is potent to modulate CD4+ T cell biology. Human umbilical vein endothelial cells were cultutred in presence of 1 or 10 µM simvastatin or vehicle for 24 hours (duplicate conditions). Total RNA was isolated and RNA-seq libraries were prepared using 8-bp barcodes with standard Illumina adaptors.

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2021-10-30
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