Crystal structure of MERS-CoV Nsp5 in complex with PF-07817883

Crystal structure of MERS-CoV Nsp5 in complex with PF-07817883 Descriptor: 3C-like proteinase nsp5, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide Authors: Chen, P, Arutyunova, E, Lemieux, M.J. Deposit date: 2024-05-05 Release date: 2024-08-07 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.5 Å) Cite: A Structural Comparison of Oral SARS-CoV-2 Drug Candidate Ibuzatrelvir Complexed with the Main Protease (M pro ) of SARS-CoV-2 and MERS-CoV. Jacs Au, 4, 2024