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Maternal Smchd1 regulates Hox gene expression and patterning in the mouse embryo [RNAseq tailbud]

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RNAseq from somite-matched tailbud tissue from E8-8.5 embryo tailbuds at the 6-11 somite developmental stages. Our overall design is to compare between Smchd1 control and Smchd1 maternally deleted samples. We have performed RNA-seq in 37 tailbud samples from E8-8.5 mouse embryos, with 6 to 11 somites each. In all cases we compare the Smchd1 maternally deleted to the control, at the matched somite number.

本数据集包含针对发育阶段处于6~11体节的E8-8.5小鼠胚胎尾芽组织的体节匹配样本的RNA测序(RNAseq)数据。本研究的整体实验设计为对比Smchd1野生型对照样本与Smchd1母源缺失样本:我们共对37份来源于E8-8.5小鼠胚胎的尾芽样本完成了RNA测序,每份样本对应的体节数均为6~11;所有对比组均在体节数匹配的前提下,将Smchd1母源缺失样本与对照样本进行比较。

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