The hypothesis tested in the present study was that ameliorating ER stress by TUDCA could reduce the cardiac remodeling in TAC mice. Results provide important information of the genes that were up- or
BackgroundUnderstanding the basic mechanisms and prevention of any disease pattern lies mainly on development of a successful experimental model. Recently, engineered heart tissue (EHT) has been demon
Experimental models of cardiac disease play a key role in understanding the pathophysiology of the disease and developing newtherapies. The features of the experimental models should reflect the clini
Bulk RNA-seq of left ventricle (LV) samples was performed for C10 control (WT), C10 mice treated with isoproterenol, mdx control mice, mdx mice treated with isoproterenol, mdx mice treated with propra
Drosophila melanogaster is emerging as a powerful model system for the study of cardiac disease. Establishing peptide and protein maps of the Drosophila hea
