Joint models are popular for analyzing data with multivariate responses. We propose a sparse multivariate single index model, where responses and predictors are linked by unspecified smooth functions
Table S1. Annotation of genes containing SNPs associated with gene expression. Table S2. Annotation of genes containing SNPs associated with metabolite levels. Table S3. Expressed genes and numbers of
a: NCBI Build 36.b: p-value of the most significant haplotype from paper.c: SNAP search criteria: R2>0.8 SNP dataset: T (1000 Genome Pilot 1), H3 (Hapmap3), Distance limit: 10 kb, Population: CEU.d: p
Odds ratios with 95% confidence intervals in parentheses were calculated to compare each genotypic combination to the baseline of homozygosity for common allele at rs3743175 and less common allele at
Thirty four SNPs from 18 genes were included in this study. (−/−) = major homozygote genotype, (+/+) = minor homozygote genotype, (+/−) = heterozygote genotype, GW = genome wide association studies, *