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Affimer K69 - KRAS protein complex
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创建时间：
2024-01-31
相关数据集
CRYSTAL STRUCTURE OF KRAS G12D (GPPCP) IN COMPLEX WITH BI 2852
CRYSTAL STRUCTURE OF KRAS G12D (GPPCP) IN COMPLEX WITH BI 2852 Descriptor: (3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoin
Protein Data Bank Japan2024-01-17 更新100
Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor
We report the expression result for the invivo and invitro cell lines treated with MRTX1133 Overall design: We report the expression result for the invivo and invitro cell lines treated with MRTX1133
NIAID Data Ecosystem50
Crystal Structure of KRAS G12D with compound 24 (4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2S,4S,7aR)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)naphthalen-2-ol) bound
Crystal Structure of KRAS G12D with compound 24 (4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2S,4S,7aR)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-y
Protein Data Bank Japan2024-03-06 更新40
Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs
Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs Descriptor: Paxillin LD2 peptide, Protein-tyrosine kinase 2-beta Authors: Vanarotti, M, Miller, D.J, Guibao, C.C, Zheng,
Protein Data Bank Japan2023-09-13 更新70
A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)
Evaluate the safety and tolerability of sotorasib in adult subjects with KRAS p.G12C mutant advanced solid tumors. Estimate the maximum tolerated dose (MTD) and/or a recommended phase 2 dose (RP2D) in
NIAID Data Ecosystem50
