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ENCODES a protein that exhibits diacylglycerol-dependent, calcium-independent serine/threonine kinase activity; protein kinase binding; protein serine/threonine kinase binding; INVOLVED IN cellular response to platelet-derived growth factor stimulus; intracellular signal transduction; negative regulation of apoptotic process; PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; interleukin-2 signaling pathway; ASSOCIATED WITH Cardiomegaly; hypertension; type 2 diabetes mellitus; FOUND IN glutamatergic synapse; Golgi membrane; neuromuscular junction; INTERACTS WITH (R)-adrenaline; (S)-nicotine; 1,1-dichloroethene

编码一种具有二酰甘油依赖性、钙独立性丝氨酸/苏氨酸激酶活性、蛋白激酶结合、蛋白丝氨酸/苏氨酸激酶结合的蛋白;参与细胞对血小板衍生生长因子刺激的应答、细胞内信号转导、凋亡过程的负调控;参与花生四烯酸信号通路、内皮素信号通路、白细胞介素-2信号通路;与心肥大、高血压、2型糖尿病、存在于谷氨酸能突触、高尔基膜、神经肌肉接头相关;与(R)-肾上腺素、(S)-尼古丁、1,1-二氯乙烷相互作用。

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