Additional file 1 of Activation of the PI3K/AKT signaling pathway by ARNTL2 enhances cellular glycolysis and sensitizes pancreatic adenocarcinoma to erlotinib
These data include the original data of in vitro and in vivo experiments. "P VS PR" means: comparing results between GEM-resistant pancreatic cancer cells and their parental sensitive ones. "TOTAL" me
These saturating mutagenesis screens of CDK4 and CDK6 resistance to palbociclib were part of a larger study defining the landscape of ATP-competitive inhibitor resistance residues in protein kinases.
Only a small number of promising drugs target pancreatic cancer, which is the fourth leading cause of cancer deaths with a 5-year survival of less than 5%. Our goal is to develop a new biotherapeutic