官方服务：
资源简介：
ENU used to engender resistance to a combination of a MEK inhibitor and an Akt Inhibitor, expanded and characterised as separate clones.
应用场景：
创建时间：
2021-02-04
相关数据集
Autophagy and biotransformation affect sorafenib resistance in hepatocellular carcinoma
Autophagy and biotransformation affect sorafenib resistance in hepatocellular carcinoma
integrated proteome resources50
STING agonism leads to durable clinical response in an anti-PD-L1 refractory patient: Tumor antigen-specific, single cell level biomarker analyses.. STING agonism leads to durable clinical response in an anti-PD-L1 refractory patient: Tumor antigen-specific, single cell level biomarker analyses.
Background: PD-1 pathway blockade has revolutionized cancer care, but many patients do not durably benefit from these therapies. Novel treatments to engage anti-tumor immunity in this setting are need
NIAID Data Ecosystem20
Barcode Sequencing Data of Dabrafenib Resistant HT-29 Cell Line
HT-29 cells were barcoded using the CloneTracker lentiviral barcode library and then dabrafenib resistant derivative of these cells were established. Five million barcoded HT-29 cells were seeded into
NIAID Data Ecosystem10
Gene expression in xenograft tumors derived from HCT116 and its oxaliplatin resistant clones. Gene expression in xenograft tumors derived from HCT116 and its oxaliplatin resistant clones
To explore the mechanisms associated with oxaliplatin resistance, we compared gene expression in xenograft tumors derived from human colorectal cancer tumor cells HCT116 and its oxaliplatin resistant
NIAID Data Ecosystem30
Drug Resistance Missense Mutations in Cancer Are Subject to Evolutionary Constraints
Several tumour types are sensitive to deactivation of just one or very few genes that are constantly active in the cancer cells, a phenomenon that is termed ‘oncogene addiction’. Drugs that target the
NIAID Data Ecosystem10
