The siRNA seed region is divided into two functionally different domains in RNA interference in response to 2´-OMe modifications
收藏NIAID Data Ecosystem2026-03-13 收录
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To investigate effects of siRNA with 2'-O-methyl (2'-Ome) modifications on genome-wide off-targetat, we analyzed gene expression profile of HeLa cells transfected by their siRNAs. Total RNAs were extracted from HeLa cells transfected by unmodified or 2'-O-methyl (2'-Ome) modified siRNA and performed microarray analysis.
创建时间：
2022-01-13
