Lysine residues can be post-translationally modified by various acyl modifications in bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and succinylation, were chang
As a new type of post-translational modification (PTM), lysine 2-hydroxyisobutyrylation (Khib) was firstly identified in histones and functioned as a regulator of transactivation in mammals. However,
Lysine 2-hydroxyisobutyrylation , a recently discovered post-translational modification, plays a key role in the regulation of diverse cellular processes. Botrytis cinerea is a destructive necrotrophi
In this study, we investigated the role of p300 in mediating a novel protein lysine acylation, lysine 2-hydroxyisobutyration (Khib), as well as its functional impact on cellular glucose metabolism. Us