Beta-lactam polyspecificity in E. coli
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This image dataset supports the findings in our manuscript entitled Morphological deconvolution of beta-lactam polyspecificity in <em>E. coli. </em> The images display fluorescently-labeled <em>E. coli</em> strains subjected to compound treatment at multiple concentrations. Cells were imaged in 96-well plates at 100X magnification. Our novel method for preparing <em>E. coli </em>cells for imaging enabled us to use commercially-available plate-based, automated HCI microscopes. We used the images to build our deep neural network classifier to identify bacterial morphologies as well as our Hidden Markov models for target deconvolution.
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Zenodo创建时间：
2019-05-20
