Sphingosine 1-phosphate (S1P), a pro-tumor survival bioactive lysophospholipid, generated by sphingosine kinase 1 (SphK1), regulates lymphocyte egress into circulation via transducing S1P receptor 1 (

NIAID Data Ecosystem10

Interleukin-4 Diminishes CD8(+) Respiratory Syncytial Virus-Specific Cytotoxic T-Lymphocyte Activity In Vivo

呼吸道免疫调节

T细胞功能调控

Although interleukin-4 (IL-4) has been implicated in respiratory syncytial virus (RSV)-enhanced disease, the mechanism by which it modulates immune responses to primary RSV infection remains unclear.

PubMed Central00

Additional file 8 of Differential expression of zinc finger CCHC-type superfamily proteins in thyroid carcinoma and their associations with tumor immunity

甲状腺癌分子机制

肿瘤免疫学

Supplementary Material 8: Table S8. Tumor stemness differences in THCA and their correlation with ZCCHC12

Figshare2024-08-14 更新20

The hyperconnected 3D clique at the Ets1 locus is required for T cell function (CUT&RUN)

三维基因组学

T细胞功能调控

The spatiotemporal control of gene-expression programs relies on selection and nuclear organization of enhancers. Despite mounting evidence on the formation of multi-enhancer hubs with extensive spati

NIAID Data Ecosystem00

Effect of depletion of LRIG1 on CD8+ tumor infiltrating T cells

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