The dynamic transcriptional landscape of the early chick embryo

Defining the dynamic transcriptome of the early embryo at high resolution would assist greatly in understanding vertebrate development. The chicken embryo is a long-established model system for vertebrate embryological studies, and, in combination with advanced single-molecule long-read isoform sequencing (Iso-Seq) technology, enables the dynamic transcription landscape of early vertebrate development to be studied in detail. We have generated large transcriptomic profiles reflecting the time course of chicken embryonic development from day 1 to day 8 of incubation: a period encompassing, gastrulation, somitogenesis and organogenesis.