we evaluated the mechanism behind NOTCH activation in prostate cancer Overall design: GEP analysis of mice WT, Pten pc+/+; Ptenpc-/-; Ptenpc-/- treated with Gamma-secretase inhibitor
Heterosis has been used widespread in agriculture, but its molecular mechanism is inadequately understood. Plants have a large number of non-coding RNAs (ncRNAs), among them, functional ncRNAs that ha
Identify LXR target gens that are involved in migration and invasion phenotype Overall design: PC3 prostate cancer cell were treated for 24h with DMSO or GW3965 1µM in RPMI-1640, L-Glu 2mM after overn
As the third most common cancer and the second leading cause of cancer death worldwide, colorectal cancer (CRC) poses a serious threat to people’s health. In recent years, circRNA has been widely repo
Numerous differentially expressed circular RNAs (circRNAs) have been identified; however, their roles have not been fully elucidated. Since dysregulated circRNAs may have clinical applications, it is
