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2020-06-25
相关数据集
Genome-wide CRISPR screen reveals a key role for integrin avb3 in TH2 cell polarisation [CRISPRscr]
T helper 2 (TH2) cells play critical roles in protective immunity against parasitic helminth infections and in tissue repair. However, misdirected TH2 cell responses promote allergy and asthma. Using
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CRISPR screen of B cell receptor-controlled adhesion
To find novel kinases involved in the B cell receptor - integrin axis, we performed a CRISPR screen with the kinome-centered Brunello library in an adhesion assay, in which Namalwa cells were stimulat
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Drug resistance profiling of thousands of Src kinase mutants uncovers a regulatory network that couples autoinhibition to catalytic domain dynamics. Drug resistance profiling of thousands of Src kinase mutants uncovers a regulatory network that couples autoinhibition to catalytic domain dynamics
Protein kinase inhibitors are effective cancer therapies, but acquired resistance often limits clinical efficacy. Despite the cataloguing of numerous resistance mutations with model studies and in the
NIAID Data Ecosystem60
Candida glabrata raw sequence data
Invasive candidiasis caused by non-albicans species has been on the rise in recent years, with Candida glabrata being the second most common etiological agent. Currently, we have limited knowledge abo
NIAID Data Ecosystem80
Functional genomics identified novel genes involved in growth at low temperatures in Listeria monocytogenes
Tn-seq results of mutant library at 16 and 37
NIAID Data Ecosystem70
