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Divergent transcriptional regulation of astrocyte reactivity across disorders. Divergent transcriptional regulation of astrocyte reactivity across disorders

NIAID Data Ecosystem2026-03-13 收录

星形胶质细胞转录组

跨疾病比较分析

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA820189 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2022-03-26

星形胶质细胞转录组

唐氏综合征氧化应激

We performed a broad-spectrum microarray analysis using mRNA from 3 NL and 5 DS astrocyte cultures. The microarray output was validated for several genes To explore the relation between gene expressio

NIAID Data Ecosystem40

Next generation RNA sequencing of Aβ-treated primary cultured mouse astrocytes to study the effect of ODC1 inhibition on AD-like astrocytes. Next generation RNA sequencing of Aβ-treated primary cultured mouse astrocytes to study the effect of ODC1 inhibition on AD-like astrocytes

阿尔茨海默病分子机制

星形胶质细胞转录组

Purpose: The existence and role of the urea cycle has not been well studied in the astrocytes of Alzheimer's Disease (AD). In the past, ODC1-inhibitor DFMO (Diflouromethylornithine) has been shown to

NIAID Data Ecosystem30

Astrocyte-specific transcriptome responses to chronic ethanol consumption

星形胶质细胞转录组

神经毒性机制

Purpose: Traditional whole-tissue sequencing approaches do not fully capture brain cell-type specific effects of chronic alcohol. Therefore, the purpose of this study was to identify the specific tran

NIAID Data Ecosystem20

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes. Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes

星形胶质细胞转录组

I型干扰素

Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare Wild Type astrocytes transcriptome profiling (RNA-seq) to AXL-/-

NIAID Data Ecosystem30

Transcriptional profiling of astrocytes in the prefrontal cortex, hippocampus, accumbens nucleus and caudate putamen of a Aldh1l1-TRAP (JD130) mouse line after chronic social defeat stress

抑郁症分子机制

星形胶质细胞转录组

Psychiatric disorders, especially major depressive disorder, are prominent cause of disability worldwide, and in dire need of better diagnostic and therapeutic tools. In order to identify the cellular

NIAID Data Ecosystem20

Divergent transcriptional regulation of astrocyte reactivity across disorders. Divergent transcriptional regulation of astrocyte reactivity across disorders

资源简介：

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