Receiver operating characteristic (ROC) curve analyses for the lowest median neutralization values of YFV-, MAYV, CHIKV-infected groups compared to the highest median neutralization values of respective mock groups.

Legend: Lowest (for infected groups) and highest (for mock groups) median neutralization values using liver homogenates in adapted plaque reduction neutralization assays were used for ROC analyses. Samples were grouped (n = 12; 6 infected + 6 mock) and compared by dilution. Analyses were made for each virus separately and considering all data together (n = 36). YFV: Yellow fever virus, MAYV: Mayaro virus, CHIKV: Chikungunya virus. AUC: area under the curve. dil: dilution. Analyses were carried out with Graph PadPrism 8.0.2. The asterisks indicate statistical significance. (XLSX)