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Supplementary Table S4 from Resistance to Durvalumab and Durvalumab plus Tremelimumab Is Associated with Functional <i>STK11</i> Mutations in Patients with Non–Small Cell Lung Cancer and Is Reversed by STAT3 Knockdown

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NIAID Data Ecosystem2026-04-30 收录
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Marker genes for the main CD45+ cell populations identified in Supplementary Figure 5. Only genes with adjusted p-value < 0.01 and average log fold-change > 0.3 were included. gene, gene name; p_val, p-value calculated based on Wilcoxon test; avg_logFC, log fold-change of the average expression between the given cluster and all other clusters; pct.1, fraction of gene-expressing cells in the given cluster; pct.2, fraction of gene-expressing cells in all other clusters; pct.diff, Difference between the percentage of gene-expressing cells in the given cluster and all other clusters; p_val_adj, Bonferroni adjusted p-value; cluster, cluster annotation based on the gene markers identified; resolution, clustering resolution parameter used in Seurat.

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2021-11-01
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