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antiviral RNAi in mammals. Homo sapiens

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NIAID Data Ecosystem2026-03-10 收录
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In vertebrates, recognition of viral RNA induces a sophisticated type I interferon (IFN)-based immune response, and it has been proposed that this response masks or inhibits antiviral RNAi. To test this hypothesis, we analyzed viral small RNA production in differentiated cells deficient in the cytoplasmic RNA sensors RIG-I and MDA5.

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2017-08-06
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