We analyzed the transcriptional consequences of the BET bromodomain inhibitor JQ1 in the T-ALL cell line LOUCY by microarray analysis. Sustained exposure at a high concentration (48h, 1µM) revealed br
Enhancer elements are a key regulatory feature of many important genes. Several general features including the presence of specific histone modifications are used to demarcate potentially active enhan
Additional file 5: Table S4. Supporting information related to SCENIC analysis. Summary of regulons discovered in healthy BM B-lineage analysis (related to Fig. 2) and the related validation motif ana