Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors

Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors Descriptor: (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG family molecular chaperone regulator 1, ... Authors: Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. Deposit date: 2009-01-26 Release date: 2009-03-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009