Genotype frequencies in Asian and Caucasian populations.

The genotype frequencies of CYP, PON1 Q192R, and ABCB1 C3435T in normal Han Chinese population (n = 92) and normal Caucasian population (n = 92) are shown. Normal Han Chinese population has a higher CYP 2C19*2 mutant allele carrier rate (12% for *2/*2 and 19% for wt/*2) than that of the Caucasian population (2.2% for *2/*2 and 22.8% for wt/*2). The Han Chinese population also showed higher PON1 Q192R mutant allele carrier rate (80.1%; 44.5% for RR192 and 35.9% for QR192) than that in Caucasian population (35.9%; 4.4% for RR192 and 31.5% for QR192).